Steve Braunstein MD PhD

Graduated in 2014

Steve Braunstein MD PhD

 

 

 

 

 

 

 

 

  

Educational Background 

Radiation Oncology Residency, University of California San Francisco (2010-2014)      

Internship, Internal Medicine, Brigham and Women’s Hospital, Boston (2010)

M.D. Ph.D., New York University School of Medicine, New York (2009)

Awards & Honors

UCSF Exceptional Physician Award (2013)

UCSF Resident QI Champion (2013)

UCSF Patient Care Fund Grant (2012)

AOA Inductee (2008)

Honors in Doctoral Dissertation (2008)

NYC Urban Health Initiative Grant  (2003)

CUNY Jonas Salk Medical Scholarship (1998)

HHMI Undergraduate Student Research Fellowship (1997)

Phi Beta Kappa Inductee (1997)

Presidential Full Tuition College Scholarship (1996) 

Selected Publications and Abstracts

Braunstein S, Nakamura JL. Radiotherapy-induced malignancies:  Review of clinical features, pathobiology and evolving approaches for mitigating risk. Front Oncol 2013 Apr;3:73. PMID 23565507.

Nie K, Chuang C, Kirby N, Braunstein S, Pouliot J. Site-Specific Deformable Imaging Registration (DIR) Algorithm Selection Using Patient-Based Simulated Deformations. Med Phys 2013 Apr; 40(4). PMID 23556905.

Choi G, Huang B, Pinarbasi E, Braunstein S, Horvai A, Kogan S, Bhatia S, Faddegon B, Nakamura JL. Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumor modeling second malignant neoplasms.Cancer Res 2012 Dec;72(24):5425-34. PMID 23071067.

Badura M, Braunstein S, Zavadil J, Schneider RJ. DNA damage and eIF4GI in breast cancer cells reprogram translation for survival and DNA repair mRNAs. PNAS. 2012 Nov;109(46):18767-72. PMID 23112151.

Ramirez-Valle F, Badura ML, Braunstein S, Narasimhan M, Schneider RJ.Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation. Mol Cell Biol. 2010 Jul;30(13):3151-64. PMID: 20439490.

Braunstein S, Badura ML, Xi Q, Formenti SC, Schneider RJ. Regulation of protein synthesis by ionizing radiation. Mol Cell Biol. 2009 Nov; 29(21):5645-5656. Cited in Pubmed; PMID: 19704005

Matsumura S, Wang B, Kawashima N, Braunstein S, Badura M, Cameron TO, Babb JS, Schneider RJ, Formenti SC, Dustin ML, Demaria S. Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells. J Immunol. 2008 Sep; 181(5): 3099-3107. PMID: 18713980.

Ramírez-Valle F, Braunstein S, Zavadil J, Formenti SC, Schneider RJ. eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy. J Cell Biol. 2008 Apr; 181(2): 293-307. PMID: 18426977.

Braunstein S, Formenti SC, Schneider RJ. Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells. Mol Cancer Res. 2008 Jan; 6(1): 78-88. PMID: 18234964.

Braunstein S, Karpisheva K, Pola C, Goldberg J, Hochman T, Yee H, Cangiarella J, Arju R, Formenti SC, Schneider RJ. A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer. Mol Cell. 2007 Nov; 28(3): 501-512. PMID: 17996713.

Oxelmark E, Roth J, Brooks P, Braunstein S, Schneider R, Garabedian M. The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion. Mol Cell Biol. 2006 Jul; 26(14): 5205-5213. PMID: 16809759.

Connolly E, Braunstein S, Formenti S, Schneider RJ. Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells. Mol Cell Biol. 2006 May; 26(10): 3955-3965. PMID: 16648488.

Kim S, Zhang R, Braunstein S, Joachimiak A, Cvekl A, Hegde RS. Structure of the retinal determination protein Dachshund reveals a DNA binding motif. Structure. 2002 Jun; 10(6): 787-795. PMID: 12057194.

Braunstein S, Deramaudt T, Rosenblum D, Dunn M, Abraham NG. Heme oxygenase-1 gene expression as a stress index to ocular irritation. Curr Eye Res. 1999 Aug; 19(2): 115-122. PMID: 10420180.

Deramaudt B, Braunstein S, Remy P, Abraham NG. Gene transfer of human heme oxygenase into coronary endothelial cells potentially promotes angiogenesis. J Cell Biochem. 1998 Jan; 68(1): 121-127. PMID: 9407320.

Presentations

Braunstein S, Zakhireh J, Halberg F, Hwang S, Park C, Fowble B. Outcome in Women with Ductal Carcinoma In Situ (DCIS) > 4 cm Treated with Breast Conservation Therapy. Accepted for presentation at ASTRO September 2013; Atlanta, GA.

Braunstein S, Dayal M, Tinkle C, Chang J, Kaur G, Perez-Andujar, Chaung C, Ma L, Parsa A, Barani I. Benefit of Adjuvant Radiotherapy in Management of Recurrent Atypical Meningioma. Accepted for presentation at ASTRO September 2013; Atlanta, GA.

Braunstein S, Mroue R, Huang B, Bandyopadhyay S, Nakamura J. Operational Signaling Pathways in Radiation-Induced Tumors. Accepted for presentation at Children’s Tumor Foundation Neurofibromatosis Meeting June 2013; Monterey, CA.

Braunstein S, Silveira W, Alexander, J, Anwar M, Haas-Kogan D, Fogh S.Increasing Compliance With Documentation Using Modern Electronic Health Record Systems Towards Quality Improvement in Radiation Practice Medical Coding. Accepted for presentation at ASTRO September 2013; Atlanta, GA.

Braunstein S, Mroue R, Huang B, Bandyopadhyay S, Nakamura J. TumorSensitivity Profiles in an Nf1 Mutant Mouse Model System Using a Drug Sensitivity Screen. Poster presentation at Children’s Tumor Foundation Neurofibromatosis Meeting June 2013; Monterey, CA.

Braunstein S, Lometti M, Pinnaduwage D, Chuang C, Yom S, Gottschalk A, Descovich, M. Evaluation of dose differences and clinical outcomes between Ray Tracing and Monte Carlo algorithms for SABR treated lung tumors. Poster presentation at: ASCO-ASTRO Lung September 2012; Chicago, IL.

Braunstein S, Glastonbury CM, Quivey JM,  Weinberg VK, Chen J, Yom SS.The Contribution of Specialized Diagnostic Radiology in Head and Neck Radiation Treatment Planning. Poster presentation at: ASTRO June 2011; Miami, FL.

Braunstein S, Xi Q, Formenti S, Schneider R. Ionizing radiation controls protein synthesis through a novel akt-independent pathway involving regulation. Oral presentation at: RRS-ASTRO October 2005; Denver, CO.

Braunstein S, Formenti SC, Schneider RJ. Alteration of Translational Control Pathways Potentiates Angiogenesis and Survival in Breast Cancer Cell Lines. Oral presentation at: NY Academy of Science Cancer Meeting June 2005; New York, NY.

Braunstein S, Formenti SC, Schneider RJ. Resistance To Radiation Cytotoxicity In Breast Carcinomas Requires Protein Synthesis And Is Mediated Specifically By Elevated Levels Of Initiation Factor eIF4G. Oral presentation presented at: ASTRO October 2004; Atlanta, GA. 

Braunstein S, Connolly E, Schneider RJ. Alteration of Translation Factors in Breast Carcinoma. Poster presentation at: Translational Control Meeting September 2002; Cold Spring Harbor, NY.