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Alexei Polishchuk MD PhD

PGY4

Alexei Polishchuk MD PhD

 

 

 

 

 

 

 

 

  

Educational Background 

Radiation Oncology Residency, University of California San Francisco (2012-2016)    

Internship, Albert Einstein Medical Center, Philadelphia, PA (2012)      

Ph.D., Biochemistry & Mol. Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA (2005-2009)

M.D., University of Pennsylvania School of Medicine Combined Degree Program, Philadelphia, PA. (2003-2011)

Awards & Honors

 

 

 

O.H. Perry Pepper Prize, University of Pennsylvania (2011)

Alpha Omega Alpha, University of Pennsylvania (2011)

Medical Student Fellowship in Radiation Oncology, UCSF (2010)

Michael Harty Award in Gross Anatomy, University of Pennsylvania (2004)

Everett Wallis Prize in Organic Chemistry, Princeton University (2003)

Member, Phi Beta Kappa, Princeton University (2003)

William Foster Prize in Chemistry, Princeton University (2002)

Manfred Pyka Prize in Physics, Princeton University (2001)

President’s Award for Academic Achievement, Princeton University (2000) 

Selected Publications and Abstracts

Rogers JMG,* Polishchuk AL,* Guo L,* Wang J, DeGrado WF, Gai F. (2011)Photoinduced electron transfer and fluorophore motion as a probe of the conformational dynamics of membrane proteins: application to the influenza A M2 proton channel. Langmuir 27(7), 3815-3821.

Polishchuk AL, DuBois SG, Haas-Kogan D, Hawkins R, Matthay KK (2011)Response, survival and toxicity after 131I-MIBG therapy for neuroblastoma in pre-adolescents, adolescents and adults. Cancer 117(18), 4286-4293.

Polishchuk AL, Lear JD, Ma C, Lamb RA, Pinto LH, DeGrado WF (2010) A pH-dependent conformational ensemble mediates proton transport through the influenza A/M2 protein. Biochemistry 49(47), 10061-10071.

Acharya R,* Carnevale V,* Fiorin G,* Levine BG,* Polishchuk AL,* Balannik V, Samish I, Lamb RA, Pinto LH, DeGrado WF, Klein ML (2010) Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus. Proc. Natl. Acad. Sci. U.S.A. 107(34), 15409-15414.

Ma C,* Polishchuk AL,* Ohigashi Y, Stouffer AL, Schon A, Magavern E, Jing X, Lear JD, Freire E, Lamb RA, DeGrado WF, Pinto LH (2009) Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel. Proc. Natl. Acad. Sci. U.S.A. 106(30), 12283-12288.

Nguyen PA, Soto CS, Polishchuk A, Caputo GA, Tatko CD, Ma C, Ohigashi Y, Pinto LH, DeGrado WF, Howard KP. (2008) pH-induced conformational change of the influenza M2 protein C-terminal domain. Biochemistry 47(38), 9934-9936.

Weeks CL, Polishchuk A, Getahun Z, DeGrado WF, Spiro TG. (2008)Investigation of an unnatural amino acid for use as a resonance Raman probe: detection limits and solvent and temperature dependence of the nCN band of 4-cyanophenylalanine. J. Raman Spectrosc. 39(11) 1606-1613.

Polishchuk AL, Bartlett KL, Friedman LA, Jones M, Jr. (2004), A p-benzyne to m-benzyne conversion through a 1,2-shift of a phenyl group. Completion of the benzyne cascade. J. Phys. Org. Chem. 17(9), 798-806.

* - Authors contributed equally to this work.